Ketamine Infusion Clinics vs Ketamine Assisted Therapy Understanding Their Benefits and Therapeutic Frameworks
- Nasima Laczynski
- Jan 20
- 3 min read
Ketamine has gained attention as a promising treatment for depression, anxiety, PTSD, and other mental health conditions. It is important to understand there are different mental health treamtment interventions that use ketamine- they may sound the same but actually differ from one anther. Two common interventions will be explained in this article: ketamine infusion treatments and ketamine assisted therapy. While both use ketamine to support healing, they differ in how the treatment is delivered and integrated into a broader therapeutic process. Understanding these differences can help individuals choose the approach that best fits their needs.

Ketamine Infusion Treatments
Ketamine infusion clinics typically focus on administering ketamine intravenously in a controlled medical setting. The main goal is to provide rapid relief from symptoms, especially for treatment-resistant depression or severe anxiety. Patients receive a series of ketamine infusions over days or weeks, monitored by medical staff.
Treatment focus: Primarily symptom reduction through ketamine’s pharmacological effects.
Session structure: Patients usually lie down quietly during infusions, with minimal interaction.
Therapeutic support: Limited or no ongoing psychotherapy during or immediately after infusions, and typically minimal integration support regarding psychological or emotional material that surfaces.
Benefits: Fast-acting relief, especially for acute depressive episodes or suicidal thoughts.
This approach can be life-changing for people who have not responded to traditional medications. The ketamine quiets the brain’s default mode network, which is often overactive in depression, allowing new neural connections to form. However, without additional therapy, the experience may not fully address underlying emotional or psychological issues.
What Is Ketamine Assisted Therapy?
Ketamine assisted therapy (KAT) combines ketamine administration with psychotherapy in a more integrated and relational framework. Instead of just receiving infusions, patients engage in therapeutic sessions before, during, and after ketamine use.
Treatment focus: Healing through both ketamine’s neurochemical effects and therapeutic processing.
Session structure: Therapy sessions are designed around ketamine experiences, often including talk therapy, guided imagery, or other modalities.
Therapeutic support: A therapist provides relational support during ketamine sessions, helping patients navigate emotions and insights.
Integration: Post-session integration helps patients make sense of their experiences and apply insights to daily life.
KAT often uses other therapeutic tools alongside ketamine, such as EMDR (Eye Movement Desensitization and Reprocessing), parts work, or somatic therapies. These methods can be especially effective when the brain’s default mode network is quieted by ketamine, allowing deeper access to trauma and emotional material.
How Ketamine Assisted Therapy Supports Attachment and the Nervous System
One key advantage of ketamine assisted therapy is the relational support provided during sessions. Many mental health challenges stem from early attachment wounds or nervous system dysregulation. The presence of a compassionate therapist during ketamine sessions can create a safe space for healing these core issues.
Attachment healing: The therapist’s attuned presence can help repair disrupted attachment patterns.
Nervous system regulation: Guided breathing, grounding, and somatic techniques during sessions support nervous system balance.
Emotional processing: Patients can explore difficult feelings with support, reducing overwhelm.
Accelerated progress: The quieting of the default mode network allows patients to access and process material that may be harder to reach in regular therapy.
This relational aspect makes KAT a powerful option for those seeking not just symptom relief but deeper emotional healing and growth.
Benefits of Both Approaches
Both ketamine infusion clinics and ketamine assisted therapy offer valuable benefits depending on individual needs.Choosing between these options depends on treatment goals. For immediate symptom relief, infusion clinics may be ideal. For those wanting to explore trauma, attachment, and emotional growth, ketamine assisted therapy offers a richer experience.
Practical Considerations When Choosing a Treatment
Medical history: Infusion clinics often require medical clearance and focus on safety during ketamine administration.
Therapeutic goals: Clarify if you want symptom relief alone or deeper psychological work.
Availability: KAT may require more time commitment and access to trained therapists.
Cost: Therapy combined with ketamine sessions can be more expensive but may offer longer-lasting benefits.
Comfort level: Some may prefer the medical setting of infusion clinics, while others seek the relational environment of KAT.
Final Thoughts on Ketamine Treatments
Ketamine offers new hope for many struggling with mental health challenges. Understanding the difference between ketamine infusion clinics and ketamine assisted therapy helps individuals make informed choices. While infusion clinics provide fast symptom relief, ketamine assisted therapy adds relational support, integration, and the use of other therapeutic tools to deepen healing.
If you are considering ketamine treatment, think about your goals and what kind of support you want during the process. Discuss options with qualified providers to find the best fit. With the right approach, ketamine can be a valuable part of a larger healing journey.
Nasima Laczynski, LPC



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